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3 Rifle Cartridges to Hunt the World

From varmints to African dangerous game, contributor Philip Massaro takes a closer look at three groups of cartridges that cover the entire spectrum.

Dangerous Domestic Game

You don't have to go international to find dangerous game. Keith Wood takes a closer look at some of more imposing prey that can be found right here in the United States.

Behind the Bullet: .450 Nitro Express

Despite its rarity today, we all owe the .450 Nitro Express a debt of gratitude for the simple fact that it established a ballistic formula upon which so many dangerous game hunters rely.

Head to Head: .450 Nitro Express vs. .470 Nitro Express

While both are excellent choices for an all-around dangerous game cartridge, which offers the best performance for hunters? Contributor Philip Massaro takes a closer look at what makes each cartridge tick.

Head to Head: .404 Jeffery vs. .416 Rigby

While both cartridges have a rather impeccable reputation, which makes a better choice for the dangerous game hunter? Contributor Philip Massaro takes a closer look at what makes each cartridge tick.

Boers, Big Bullets and Buffalo

Big-bore lever-action rifles have the ammo capacity, dependability and speed to be considered ideal African dangerous-game rifles, as long as you do your part.

Behind the Bullet: .404 Jeffery

Why would a dangerous game hunter choose a .404 Jeffery over a .416 or a .375 H&H? Well, because it’s really cool. Let Philip Massaro explain.

Behind the Bullet: .416 Ruger

Introduced in 2008, the .416 Ruger is the only commercially produced cartridge in that .416-inch bore diameter designed to fit in a long-action receiver, making it an ideal choice for dangerous game.

New for 2025: Christensen Arms Evoke .375 H&H

Christensen Arms has unveiled the Evoke .375 H&H, the newest addition to its esteemed Evoke rifle series. Chambered in the legendary .375 Holland & Holland Magnum, this rifle is the ultimate choice for hunters chasing the biggest and most dangerous game around the globe.

Behind the Bullet: .375 H&H Magnum

The .375 bore is the legal minimum for dangerous game in many African countries, and with good reason: it generates just over 4,000 ft.-lbs. of energy at the muzzle, and offers a bullet with enough Sectional Density to get the job done, and done well.

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