Driving a 40-grain bullet at a muzzle velocity of between 1875 and 1910 fps, if you desire to pursue furbearers and varmints at ranges beyond what the .22 LR can handle, the .22 WMR is your cartridge.
If you like the idea of the full-diameter hole and heavyweight punch that an old, full-patch “punkin' ball” can deliver, you’ll want to take a hard look at Ddupleks slugs.