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The pursuit of Cape buffalo in Tanzania’s Selous Game Reserve is a bucket-list hunt.

Introduced in 2008, the .416 Ruger is the only commercially produced cartridge in that .416-inch bore diameter designed to fit in a long-action receiver, making it an ideal choice for dangerous game.

Despite its rarity today, we all owe the .450 Nitro Express a debt of gratitude for the simple fact that it established a ballistic formula upon which so many dangerous game hunters rely.

The .375 Ruger is simple, effective, affordable and shootable, and truly mirrors the velocities of the H&H case in a cartridge housed in a standard long action with a beltless, rimless design.

Introduced in 1989, the .416 Remington Magnum is fully capable of handling any and all game, including the heavyweights like elephant, hippo, buffalo and coastal brown bears. Its trajectory is flatter than most would think, and recoil isn’t much heavier than the .375 H&H, yet the terminal results are visibly greater.

Is it worthwhile for the hunter looking for a .375 to choose the Ruger over the older, timeless .375 H&H Magnum? Contributor Philip Massaro examines the pros and cons of each cartridge.

Introduced in 1956, the .458 Winchester Magnum offered the ballistic formula of the .450 NE in a bolt-action, affordable rifle.

The cartridge’s sheer size, steep shoulder and Rigby name all add up to a century-plus-old classic that isn’t going anywhere anytime soon.

Contributor Philip Massaro shares some of his favorite rifles and loads for different bear hunting scenarios.