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What Winchester sought to do in 1958 was to provide those hunters who pursued the great bears and larger cervids of North America with a perfect choice for their endeavors, as well as developing one the most logical choices for an African light rifle. The result? The .338 Win. Mag.

The .240 Weatherby Magnum is the fastest 6mm on the commercial market, exceeding the muzzle velocity of the .243 Win. and 6mm Rem. by 300 fps. If you’re the hunter who likes obscure cartridges, the .240 Wby. Mag. is a great choice for deer, pronghorn and similar-sized game.

Both cartridges are fully capable of taking the full range of North American game, and are a solid choice for a light rifle on safari. Therefore, which is the better choice for the hunter looking for a .300 magnum? 

Introduced in 2008, the .416 Ruger is the only commercially produced cartridge in that .416-inch bore diameter designed to fit in a long-action receiver, making it an ideal choice for dangerous game.

Each shooter’s recoil tolerance level is different, and some people appreciate flexibility over specific application, but these five cartridges will cleanly take any dangerous-game animal on earth.

One is a newbie and the other ranks among the most popular hunting cartridges sold to this day, but both have appreciable characteristics. Which cartridge is the better choice for the hunter? Here’s a detailed look at the pros and cons of each.

Weatherby announces two Mark V Backcountry rifles in combination with an all-new magnum cartridge; the 6.5 Weatherby RPM (Rebated Precision Magnum).

With respect to overall performance and ammunition availability, here are the five best all-around cartridges for North American big-game species.